Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.50 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11738091 | 0.77 | ALDH1A1 (0.54) | ALDH1A1ALDH1A2ALDH2ALDH1A3KMT2A | |
| SCHEMBL7346035 | 0.76 | — | — | |
| SCHEMBL7765744 | 0.75 | ALDH1A1 (0.50) | ALDH1A1ALDH1A2ALDH2ALDH1A3KMT2A | |
| SCHEMBL10959241 | 0.75 | ALDH1A1 (0.50) | ALDH1A1ALDH1A2ALDH2ALDH1A3KMT2A | |
| SCHEMBL7771102 | 0.75 | ALDH1A1 (0.32) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL7557327 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KMT2ALMNAMAPTPTGS2 | |
| SCHEMBL9579112 | 0.71 | DPP4 (0.43) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL9579117 | 0.71 | DPP4 (0.43) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL10915792 | 0.70 | — | — | |
| SCHEMBL10746266 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |