Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminomethylbenzoic Acid SCHEMBL29271526 | 0.88 | ALDH1A1 (0.59) | ALDH1A1KMT2ALOXL2MEN1CYP1A2 | |
| Aminomethylbenzoic Acid SCHEMBL11755138 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KMT2ALOXL2MEN1HDAC3 | |
| Aminomethylbenzoic Acid SCHEMBL38758 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KMT2ALOXL2MEN1HDAC3 | |
| Aminomethylbenzoic Acid SCHEMBL9344424 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KMT2ALOXL2MEN1HDAC3 | |
| Aminomethylbenzoic Acid SCHEMBL28342619 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2ALOXL2MEN1HDAC3 | |
| Aminomethylbenzoic Acid SCHEMBL1206230 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2ALOXL2MEN1HDAC3 | |
| Aminomethylbenzoic Acid SCHEMBL7428232 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2ALOXL2MEN1HDAC3 | |
| Aminomethylbenzoic Acid SCHEMBL1567841 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2ALOXL2MEN1HDAC3 | |
| Aminomethylbenzoic Acid SCHEMBL7422142 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KMT2ALOXL2MEN1CYP1A2 | |
| SCHEMBL1851387 | 0.80 | HRH3 (0.61) | ALDH1A1KMT2ALOXL2MEN1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144011-A2 | PRODRUG COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | Coulter Pharmaceutical, Inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000033888-A9 | PRODRUG COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COULTER PHARM INC (US) | 2001-05-10 | — | — | WO | disclosed |
| WO-2000033888-A2 | PRODRUG COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COULTER PHARMACEUTICAL, INC. (US) | 2000-06-15 | — | — | WO | disclosed |