Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 9/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.45 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770337 | 0.94 | ADORA3 (0.43) | SYKHSP90AA1L3MBTL1AURKBINCENP | |
| SCHEMBL8596986 | 0.91 | ABL1 (0.44) | SYKNPC1RAB9AKDM4ETP53 | |
| SCHEMBL15996444 | 0.89 | HSP90AA1 (0.42) | SYKHSP90AA1L3MBTL1NPC1PKM | |
| SCHEMBL7771784 | 0.88 | HSP90AA1 (0.45) | SYKHSP90AA1L3MBTL1AURKBINCENP | |
| SCHEMBL7454751 | 0.86 | NPC1 (0.57) | SYKHSP90AA1L3MBTL1NPC1PKM | |
| SCHEMBL31260432 | 0.86 | NPC1 (0.57) | SYKHSP90AA1L3MBTL1NPC1PKM | |
| SCHEMBL8935757 | 0.84 | ADORA3 (0.43) | HSP90AA1NPC1RAB9AKDM4ETP53 | |
| SCHEMBL8597039 | 0.83 | MEN1 (0.44) | SYKHSP90AA1L3MBTL1AURKBINCENP | |
| SCHEMBL7770338 | 0.82 | FFAR1 (0.43) | SYKHSP90AA1L3MBTL1AURKBINCENP | |
| SCHEMBL7766604 | 0.81 | NPC1 (0.51) | SYKHSP90AA1L3MBTL1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248870-B1 | OLIGO-2,6-PYRIMIDINE COMPLEXING AGENT. | NYCOMED IMAGING AS (NO) | 2001-06-19 | — | — | US | disclosed |
| US-5817774-A | Unsymmetrical complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | STERLING WINTHROP INCORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5559214-A | Unsymmetrical complexing agents and targeting immunoreagents useful in thearpeutic and diagnostic compositions and methods | STERLING WINTHROP INC. (US) | 1996-09-24 | — | — | US | disclosed |