Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391451 | 0.94 | GYS1 (0.36) | PPARGPPARAKMT2AMEN1KDM4E | |
| SCHEMBL8824335 | 0.88 | ALDH1A1 (0.34) | KMT2AMEN1KDM4EALDH1A1PDE4A | |
| SCHEMBL7770333 | 0.85 | ADORA2A (0.44) | PPARGPPARAKMT2AADORA2AMEN1 | |
| SCHEMBL8597039 | 0.84 | MEN1 (0.44) | PPARGPPARAKMT2AADORA2AMEN1 | |
| SCHEMBL8601997 | 0.81 | ALDH1A1 (0.44) | KMT2AMEN1KDM4EALDH1A1GYS1 | |
| SCHEMBL7717266 | 0.78 | ADORA2A (0.37) | KMT2AADORA2AMEN1KDM4EALDH1A1 | |
| SCHEMBL30803820 | 0.78 | ADORA2A (0.37) | KMT2AADORA2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7774104 | 0.78 | ADORA2A (0.43) | ADORA2AKDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL8936038 | 0.78 | ADORA2A (0.37) | KMT2AADORA2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8765283 | 0.77 | MCL1 (0.45) | KDM4EALDH1A1GYS1TP53ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248870-B1 | OLIGO-2,6-PYRIMIDINE COMPLEXING AGENT. | NYCOMED IMAGING AS (NO) | 2001-06-19 | — | — | US | disclosed |
| US-5817774-A | Unsymmetrical complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | STERLING WINTHROP INCORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5559214-A | Unsymmetrical complexing agents and targeting immunoreagents useful in thearpeutic and diagnostic compositions and methods | STERLING WINTHROP INC. (US) | 1996-09-24 | — | — | US | disclosed |