SCHEMBL7772149

SCHEMBL7772149

CCCOC1NNC(=O)N1C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6231378 0.67 KDM4E (0.35) KDM4EGLA
SCHEMBL6231077 0.61 KDM4A (0.33) KDM4EGLA
SCHEMBL6232620 0.60 ALDH1A1 (0.31) KDM4EGLA
SCHEMBL6237163 0.58 GAA (0.42) KDM4E
SCHEMBL6232661 0.58 ALDH1A1 (0.32)
SCHEMBL23912733 0.57 FKBP1A (0.35) KDM4EGLA
SCHEMBL6232475 0.57 NPC1 (0.36) KDM4E
SCHEMBL6233114 0.55 ALDH1A1 (0.46) KDM4E
SCHEMBL10578633 0.55 ALDH1A1 (0.33) KDM4E
SCHEMBL600619 0.53 CHRM2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1113009-A1 A process for the manufacture of the salts of sulfonylaminocarbonyl triazolinones Bayer Corporation (US) 2001-07-04 EP disclosed
US-6147222-A Process for the manufacture of sulfonylaminocarbonyl triazolinones and salts thereof under pH controlled conditions BAYER CORPORATION (US) 2000-11-14 US disclosed
US-6147221-A Process for the manufacture of sulfonylaminocarbonyl triazolinones and salts thereof BAYER CORPORATION (US) 2000-11-14 US disclosed