SCHEMBL7772192

SCHEMBL7772192

CCCCNP(=S)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10873347 0.90 EPHX1 (0.44)
SCHEMBL11670299 0.83
Toluene SCHEMBL28638595 0.81 TSHR (0.38)
SCHEMBL11271487 0.80
SCHEMBL10902272 0.77 TSHR (0.32)
SCHEMBL10902864 0.75 TP53 (0.34)
SCHEMBL11778325 0.75 TSHR (0.35)
SCHEMBL3373846 0.75 TSHR (0.31)
SCHEMBL10874480 0.74
SCHEMBL409280 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0968218-A1 PREPARATION OF N-HYDROCARBYLTHIOPHOSPHORIC TRIAMIDES ALBEMARLE CORPORATION (US) 2000-01-05 EP claimed
EP-0958299-A1 RECOVERY OF N-HYDROCARBYL(THIO)PHOSPHORIC TRIAMIDES FROM REACTION MIXTURES ALBEMARLE CORPORATION (US) 1999-11-24 EP claimed
US-5883297-A FORMING THE TRIAMIDES FROM PHOSPHORYL DICHLORIDES AND AMMONIA ALBEMARLE CORPORATION (US) 1999-03-16 US claimed
WO-1998031693-A1 PREPARATION OF N-HYDROCARBYLTHIOPHOSPHORIC TRIAMIDES ALBEMARLE CORPORATION (US) 1998-07-23 WO claimed
WO-1998031691-A1 RECOVERY OF N-HYDROCARBYL(THIO)PHOSPHORIC TRIAMIDES FROM REACTION MIXTURES ALBEMARLE CORPORATION (US) 1998-07-23 WO claimed
US-5770771-A REACTING A PRIMARY HYDROCARBYL MONOAMINE, A TERTIARY AMINE AND THIOPHOSPHORYL CHLORIDE WHILE REMOVING HEAT OF REACTION; SUBSEQUENT REACTION WITH AMMONIA ALBEMARLE CORPORATION (US) 1998-06-23 US claimed
CN-122006618-A Continuous reaction equipment for N-N-butyl thiophosphoric triamide and preparation method 武威金仓生物科技有限公司 2026-05-12 CN disclosed
CN-110950904-B Continuous preparation method and preparation device for N-N-butyl thiophosphoric triamide 武威金仓生物科技有限公司 2023-05-05 CN disclosed
EP-2687536-B1 Method for producing asymmetric (thio)phosphate triamides SALTIGO GMBH (DE) 2015-12-09 EP disclosed
EP-2687536-A1 Method for producing asymmetric (thio)phosphate triamides Saltigo GmbH (DE) 2014-01-22 EP disclosed
EP-0966555-B1 INHIBITING FERROUS METAL CORROSION BY AQUEOUS AMMONIATE SOLUTIONS ALBEMARLE CORP (US) 2001-08-01 EP disclosed
EP-0975642-A1 SEPARATING AMMONIUM CHLORIDE FROM N-HYDROCARBYL(THIO)PHOSPHORIC TRIAMIDE ALBEMARLE CORPORATION (US) 2000-02-02 EP disclosed
EP-0968218-A1 PREPARATION OF N-HYDROCARBYLTHIOPHOSPHORIC TRIAMIDES ALBEMARLE CORPORATION (US) 2000-01-05 EP disclosed
WO-1998031851-A1 INHIBITING FERROUS METAL CORROSION BY AQUEOUS AMMONIATE SOLUTIONS ALBEMARLE CORPORATION (US) 1998-07-23 WO disclosed
WO-1998031693-A1 PREPARATION OF N-HYDROCARBYLTHIOPHOSPHORIC TRIAMIDES ALBEMARLE CORPORATION (US) 1998-07-23 WO disclosed
WO-1998031692-A1 SEPARATING AMMONIUM CHLORIDE FROM N-HYDROCARBYL(THIO)PHOSPHORIC TRIAMIDE ALBEMARLE CORPORATION (US) 1998-07-23 WO disclosed
US-5770771-A REACTING A PRIMARY HYDROCARBYL MONOAMINE, A TERTIARY AMINE AND THIOPHOSPHORYL CHLORIDE WHILE REMOVING HEAT OF REACTION; SUBSEQUENT REACTION WITH AMMONIA ALBEMARLE CORPORATION (US) 1998-06-23 US disclosed
EP-0119487-B1 NOVEL N-ALIPHATIC AND N,N-ALIPHATIC PHOSPHORIC TRIAMIDE UREASE INHIBITORS AND UREASE INHIBITED UREA BASED FERTILIZER COMPOSITIONS ALLIED CORPORATION (US) 1986-07-16 EP disclosed
US-4530714-A Capable of forming urea under use conditions ALLIED CORPORATION (US) 1985-07-23 US disclosed
EP-0119487-A1 Novel N-aliphatic and N,N-aliphatic phosphoric triamide urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1984-09-26 EP disclosed