Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374732 | 0.87 | — | — | |
| SCHEMBL7772192 | 0.75 | — | — | |
| SCHEMBL11271487 | 0.71 | — | — | |
| SCHEMBL10902272 | 0.68 | TSHR (0.32) | TSHR | |
| SCHEMBL10873347 | 0.67 | EPHX1 (0.44) | TSHR | |
| SCHEMBL11778325 | 0.67 | TSHR (0.35) | TSHR | |
| SCHEMBL3376705 | 0.67 | TSHR (0.31) | TSHR | |
| SCHEMBL10902864 | 0.67 | TP53 (0.34) | TSHR | |
| SCHEMBL3372484 | 0.67 | TSHR (0.31) | TSHR | |
| SCHEMBL10874480 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756125-B1 | 1,1,3,3,3-PENTAAMINO-1-OXO/THIO-1LAMBDA5,3LAMBDA5-DIPHOSPHAZ-2-ENES, METHOD FOR PRODUCING THEM AND THEIR USE AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC HYDROLYSIS OF UREA | PIESTERITZ STICKSTOFF (DE) | 2010-11-10 | — | — | EP | disclosed |
| EP-1756125-A1 | 1,1,3,3,3-PENTAAMINO-1LAMBDA5,3LAMBDA5-DIPHOSPHAZ-2-ENES, METHOD FOR PRODUCING THEM AND THEIR USE AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC HYDROLYSIS OF UREA | SKW STICKSTOFFWERKE PIESTERITZ GmbH (DE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005118602-A1 | 1,1,3,3,3-PENTAAMINO-1λ5,3λ5-DIPHOSPHAZ-2-ENES, METHOD FOR PRODUCING THEM AND THEIR USE AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC HYDROLYSIS OF UREA | SKW STICKSTOFFWERKE PIESTERITZ GMBH (DE) | 2005-12-15 | — | — | WO | disclosed |