Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610589 | 0.84 | ALDH1A1 (0.44) | HPGDTSHRFDPSMMP1MMP3 | |
| SCHEMBL2368900 | 0.84 | MEN1 (0.43) | MMP1 | |
| SCHEMBL16825124 | 0.81 | HPGD (0.46) | HPGDTSHRFDPS | |
| SCHEMBL9114214 | 0.81 | HPGD (0.44) | HPGDTSHRFDPSMMP1 | |
| SCHEMBL28826521 | 0.80 | HPGD (0.44) | HPGDTSHRFDPS | |
| SCHEMBL232550 | 0.79 | LAP3 (0.51) | HPGDTSHRFDPSCETPLAP3 | |
| SCHEMBL7631529 | 0.77 | TSHR (0.68) | HPGDTSHRCETPFOLH1 | |
| SCHEMBL915800 | 0.77 | TSHR (0.52) | HPGDTSHRCETP | |
| SCHEMBL3043405 | 0.76 | HPGD (0.52) | HPGDTSHRFDPSCETPLAP3 | |
| SCHEMBL5054716 | 0.76 | FOLH1 (0.43) | CETPFOLH1MMP1MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986811-B1 | MAGNETIC RECORDING MEDIA INCORPORATING SURFACE TREATED MAGNETIC PIGMENT | IMATION CORP (US) | 2001-08-08 | — | — | EP | disclosed |
| EP-0909298-A1 | STABILISATION OF PAINTS WITH SPIROINDANE DERIVATIVES | Ciba SC Holding AG (CH) | 1999-04-21 | — | — | EP | disclosed |
| WO-1998001507-A1 | STABILISATION OF PAINTS WITH SPIROINDANE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-01-15 | — | — | WO | disclosed |
| EP-0659188-A4 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS. | AFFYMAX TECH NV (AN) | 1995-11-22 | — | — | EP | disclosed |
| EP-0659188-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-28 | — | — | EP | disclosed |
| US-5420328-A | Esterification with alcohol and hydrolysis | AFFYMAX TECHNOLOGIES, N.V. (AN) | 1995-05-30 | — | — | US | disclosed |
| US-5359115-A | Reacting phosphonic monoester with dialkylazodicarboxylate, triphenylphosphine and secondary alcohol to form diester, hydrolyzing selective ester to form monoester, coupling an aminoacid to yield peptidylphosphonate | AFFYMAX TECHNOLOGIES, N.V. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994006808-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-03-31 | — | — | WO | disclosed |