SCHEMBL777272

SCHEMBL777272

O=S(=O)(O)c1ccc(CC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
NT5E P21589 1/20 0.42
CA2 P00918 15/20 0.40
CA1 P00915 14/20 0.40
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
POLB P06746 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777060 0.95 TSHR (0.44) TSHRALDH1A1NT5ECA2CA1
SCHEMBL778371 0.87 TSHR (0.47) TSHRALDH1A1NT5ECA2CA1
SCHEMBL28616318 0.81 TSHR (0.44) TSHRALDH1A1NT5ECA2CA1
SCHEMBL28608045 0.81 TSHR (0.48) TSHRALDH1A1NT5ECA2CA1
SCHEMBL20560555 0.80 CA2 (0.43) CA2CA1LMNASMN1; SMN2
SCHEMBL776653 0.80 TSHR (0.50) TSHRALDH1A1NT5ECA2CA1
SCHEMBL10377765 0.78 CA1 (0.41) TSHRALDH1A1NT5ECA2CA1
SCHEMBL8618196 0.74 ESR1 (0.47) ALDH1A1CA2CA1
SCHEMBL8613505 0.74 ESR1 (0.47) ALDH1A1CA2CA1
SCHEMBL1241822 0.74 ESR1 (0.47) ALDH1A1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed