SCHEMBL776653

SCHEMBL776653

O=S(=O)(O)c1ccc(CC(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
ALDH1A1 P00352 3/20 0.50
NT5E P21589 1/20 0.50
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.43
TDP1 Q9NUW8 2/20 0.41
CYP2D6 P10635 2/20 0.38
POLB P06746 1/20 0.38
PTPRZ1 P23471 1/20 0.37
CA2 P00918 6/20 0.36
CA1 P00915 4/20 0.36
CA12 O43570 2/20 0.36
CA4 P22748 2/20 0.36
CA6 P23280 2/20 0.36
CA5A P35218 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
CA14 Q9ULX7 2/20 0.36
CA5B Q9Y2D0 2/20 0.36
HSD17B10 Q99714 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778371 0.84 TSHR (0.47) TSHRALDH1A1NT5ELMNASMN1; SMN2
SCHEMBL28608045 0.81 TSHR (0.48) TSHRALDH1A1NT5ELMNASMN1; SMN2
SCHEMBL28616318 0.81 TSHR (0.44) TSHRALDH1A1NT5ELMNASMN1; SMN2
SCHEMBL777060 0.81 TSHR (0.44) TSHRALDH1A1NT5ELMNASMN1; SMN2
SCHEMBL29001852 0.81 ALDH1A1 (0.52) TSHRALDH1A1NT5ELMNASMN1; SMN2
SCHEMBL778771 0.80 LMNA (0.43) TSHRALDH1A1NT5ELMNASMN1; SMN2
SCHEMBL777272 0.80 TSHR (0.42) TSHRALDH1A1NT5ELMNASMN1; SMN2
SCHEMBL1415708 0.79 ALDH1A1 (0.43) TSHRALDH1A1TDP1CYP2D6PTPRZ1
SCHEMBL6536459 0.79 LCK (0.38) TSHRALDH1A1NT5ELMNASMN1; SMN2
SCHEMBL11100709 0.79 ESR1 (0.54) TSHRALDH1A1NT5ELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107629050-A A kind of synthetic method of pyranone compounds of the novel imidazole class containing chalcogen 河南工业大学 2018-01-26 CN claimed
US-20230203086-A1 RIBONUCLEIC ACID PURIFICATION ARES CAPITAL CORPORATION, AS AGENT 2023-06-29 US disclosed
US-11377470-B2 Ribonucleic acid purification MODERNATX, INC. (US) 2022-07-05 US disclosed
CN-108129348-A Nitrine trifluoromethoxy compound and its synthetic method 南开大学 2018-06-08 CN disclosed
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20160024140-A1 RIBONUCLEIC ACID PURIFICATION ARES CAPITAL CORPORATION, AS AGENT 2016-01-28 US disclosed
US-20160024140-A1 RIBONUCLEIC ACID PURIFICATION ARES CAPITAL CORPORATION, AS AGENT 2016-01-28 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed
US-6544717-B2 Antireflective coating TOKYO OHKA KOGYO CO., LTD. (JP) 2003-04-08 US disclosed
US-20010049072-A1 Undercoating composition for photolithographic resist HIROSAKI TAKAKO (JP) 2001-12-06 US disclosed
US-6284428-B1 FOR FORMING OF ANTIREFLECTION UNDERCOATING LAYER TO INTERVENE BETWEEN SURFACE OF SUBSTRATE AND PHOTORESIST LAYER TO BE PATTERNED IN MANUFACTURING PROCESS OF SEMICONDUCTOR DEVICES TOKYO OHKA KOGYO CO., LTD, (JP) 2001-09-04 US disclosed
US-20010018163-A1 Undercoating composition for photolithographic resist TOKYO OHKA KOGYO CO., LTD. (JP) 2001-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203086-A1 RIBONUCLEIC ACID PURIFICATION TRDMT1, POLI, NOP2 TSHR 751/4885ALDH1A1 2932/4885NT5E 173/4885
US-11377470-B2 Ribonucleic acid purification TRDMT1, POLI, NOP2 TSHR 751/4885ALDH1A1 2932/4885NT5E 173/4885
US-20160024140-A1 RIBONUCLEIC ACID PURIFICATION TRDMT1, POLI, NOP2 TSHR 751/4885ALDH1A1 2932/4885NT5E 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.