Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 11/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797121 | 0.89 | PDGFRB (0.51) | PDGFRBKITKDRPDGFRANOX1 | |
| SCHEMBL9168436 | 0.85 | SMPD3 (0.59) | SMPD3PDGFRBKITKDRAMY1A | |
| SCHEMBL22291131 | 0.85 | SMPD3 (0.59) | SMPD3PDGFRBKITKDRAMY1A | |
| SCHEMBL10353519 | 0.81 | ERN1 (0.43) | SMPD3PDGFRBKITKDRPDGFRA | |
| SCHEMBL11614979 | 0.79 | APP (0.50) | PDGFRBKITKDRNOX1AURKA | |
| SCHEMBL9331183 | 0.76 | SMPD3 (0.73) | SMPD3AMY1ANOX1TP53MAPT | |
| SCHEMBL175592 | 0.76 | SMPD3 (0.75) | SMPD3NOX1TP53MAPT | |
| Hydrochloric Acid SCHEMBL1735170 | 0.75 | SMPD3 (0.71) | SMPD3AMY1ANOX1TP53MAPT | |
| Hydrochloric Acid SCHEMBL9648176 | 0.75 | SMPD3 (0.73) | SMPD3NOX1TP53MAPT | |
| SCHEMBL7142021 | 0.75 | NOX1 (0.54) | NOX1AURKATP53MAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517327-B1 | Immunoassay with labeled hapten analogues | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0740157-A2 | Immunoassay element comprising both labeled ligand and receptors | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| US-5422271-A | Contains only one wash compartment containing wash liquid and only one passageway connecting compartment to detection site | EASTMAN KODAK COMPANY (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0603958-A1 | Improvement of the dynamic range in specific binding assays | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5055195-A | Coagulation, filtration, separation form whole blood; having two strongly polar groups separated by aromatic or heteroaroma tic rings | BOEHRINGER MANNHEIM GMBH (DE) | 1991-10-08 | — | — | US | disclosed |