Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylsulfane SCHEMBL27714827 | 0.96 | HPGD (0.60) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Diphenylsulfane SCHEMBL7109540 | 0.96 | HPGD (0.60) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Diphenylsulfane SCHEMBL27611905 | 0.96 | HPGD (0.60) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Diphenylsulfane SCHEMBL28332331 | 0.96 | HPGD (0.60) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Diphenylsulfane SCHEMBL452 | 0.96 | HPGD (0.60) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL23277364 | 0.92 | MAOA (0.62) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Diphenylsulfane SCHEMBL451795 | 0.92 | HPGD (0.56) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Diphenylsulfane SCHEMBL18043143 | 0.92 | HPGD (0.56) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Diphenylsulfane SCHEMBL9307585 | 0.92 | HPGD (0.56) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Diphenylsulfane SCHEMBL18694664 | 0.92 | HPGD (0.56) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6273875-B1 | Medical devices having improved antimicrobial/antithrombogenic properties | EDWARDS LIFESCIENCES CORPORATION | 2001-08-14 | — | — | US | disclosed |
| WO-2000009177-A9 | MEDICAL DEVICES HAVING IMPROVED ANTIMICROBIAL/ANTITHROMBOGENIC PROPERTIES | EDWARDS LIFESCIENCES CORP (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000009177-A1 | MEDICAL DEVICES HAVING IMPROVED ANTIMICROBIAL/ANTITHROMBOGENIC PROPERTIES | EDWARDS LIFESCIENCES CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |