Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | FADS1 | O60427 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769257 | 0.87 | HPGD (0.61) | HPGDNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL20490256 | 0.82 | HPGD (0.64) | HPGDNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7771326 | 0.82 | HPGD (0.73) | HPGDNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL55226 | 0.81 | HPGD (1.00) | HPGDNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9615323 | 0.79 | FADS1 (0.72) | HPGDRAB9ASMN1; SMN2ALDH1A1FADS1 | |
| SCHEMBL1260451 | 0.79 | HPGD (0.60) | HPGDNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7765642 | 0.79 | HPGD (0.60) | HPGDNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7770821 | 0.78 | HPGD (0.68) | HPGDNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7770959 | 0.77 | RAB9A (0.81) | HPGDNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7769134 | 0.77 | RAB9A (0.76) | HPGDNPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755927-B1 | DIMETHYLFURANCARBOXANILIDE DERIVATIVE | SANKYO CO (JP) | 2001-07-18 | — | — | EP | disclosed |