Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769845 | 0.91 | FAAH (0.46) | FAAHALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL7765838 | 0.87 | FAAH (0.41) | FAAHALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL8822944 | 0.82 | HDAC3 (0.38) | FAAHALDH1A1KDM4EHDAC3HDAC1 | |
| SCHEMBL7773562 | 0.81 | ALDH1A1 (0.41) | FAAHALDH1A1KDM4EPOLBHDAC3 | |
| SCHEMBL7765801 | 0.80 | ALDH1A1 (0.43) | FAAHALDH1A1KDM4EPOLBHDAC3 | |
| SCHEMBL7771569 | 0.79 | KDM4E (0.41) | FAAHALDH1A1KDM4EPOLBTHRB | |
| SCHEMBL7770074 | 0.76 | HDAC3 (0.39) | FAAHALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL7769447 | 0.76 | FAAH (0.42) | FAAHALDH1A1KDM4EHSP90AA1MAPT | |
| SCHEMBL7769331 | 0.75 | HDAC3 (0.38) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7769432 | 0.75 | HDAC3 (0.38) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |