SCHEMBL7773756

SCHEMBL7773756

O=C(O)C1=CC(=O)N(CCN2CC(C(=O)O)=CC2=O)C1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
SIRT1 Q96EB6 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4599373 0.61 GABRP (0.31) TSHR
SCHEMBL5494524 0.60
SCHEMBL4634442 0.59 INMT (0.33)
SCHEMBL31442867 0.58
SCHEMBL25430610 0.58
SCHEMBL29954545 0.57
SCHEMBL14293551 0.56
SCHEMBL28304546 0.55 ABAT (0.31) TSHR
SCHEMBL325503 0.55
SCHEMBL10449713 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724606-B1 PREPARATION OF POLY(ETHER-ESTERS) FROM TETRAHYDROFURANS AND POLYCARBOXYLIC ACIDS DU PONT (US) 2001-08-16 EP disclosed
US-5770678-A Polymerization of, and depolymerization to, cyclic ethers using selected metal compound catalysts E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-23 US disclosed
US-5635585-A POLYESTERETHER COPOLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-06-03 US disclosed
EP-0724606-A1 PREPARATION OF POLY(ETHER-ESTERS) FROM TETRAHYDROFURANS AND POLYCARBOXYLIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-07 EP disclosed
US-5541346-A DEPOLYMERIZING POLYETHER TO TETRAHYDROFURAN BY HEATING WITH METAL CATALYST CONTAINING PERFLUOROALKYLSULFONATE OR TETRAPHENYLBORATE ANION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-30 US disclosed
WO-1995011267-A1 PREPARATION OF POLY(ETHER-ESTERS) FROM TETRAHYDROFURANS AND POLYCARBOXYLIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-04-27 WO disclosed