Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773577 | 0.93 | KAT2B (0.47) | KAT2BNPC1RAB9ACASP1SMN1; SMN2 | |
| SCHEMBL7380302 | 0.90 | NPC1 (0.48) | KAT2BNPC1RAB9ACASP1SMN1; SMN2 | |
| SCHEMBL8123909 | 0.85 | CYP1A2 (0.45) | KAT2BNPC1RAB9ACASP1SMN1; SMN2 | |
| SCHEMBL7773547 | 0.83 | SMN1; SMN2 (0.43) | KAT2BNPC1RAB9ACASP1SMN1; SMN2 | |
| SCHEMBL7773573 | 0.78 | KAT2B (0.44) | KAT2BNPC1RAB9ACASP1SMN1; SMN2 | |
| SCHEMBL7773572 | 0.78 | F2 (0.44) | KAT2BNPC1RAB9ACASP1SMN1; SMN2 | |
| SCHEMBL7772066 | 0.78 | SMN1; SMN2 (0.44) | KAT2BNPC1RAB9ACASP1SMN1; SMN2 | |
| SCHEMBL7771913 | 0.77 | CASP1 (0.49) | KAT2BNPC1RAB9ACASP1SMN1; SMN2 | |
| SCHEMBL7775662 | 0.76 | KAT2B (0.43) | KAT2BNPC1RAB9ACASP1SMN1; SMN2 | |
| SCHEMBL8124061 | 0.76 | FPR1 (0.41) | RAB9AALDH1A1KDM4EMAPK1RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |