Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766672 | 0.81 | TSHR (0.45) | MAPK1TSHRCYP2C9KDM4E | |
| SCHEMBL17034727 | 0.80 | CYP2C9 (0.55) | TSHRCYP2C9MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL7766667 | 0.80 | TSHR (0.41) | MAPK1TSHRCYP2C9KDM4EHIF1A | |
| SCHEMBL6413206 | 0.79 | TRIM24 (0.46) | MAPK1TSHRKDM4EHIF1AMTNR1A | |
| SCHEMBL19944358 | 0.79 | TSHR (0.62) | MAPK1TSHRCYP2C9KDM4EMTNR1A | |
| SCHEMBL3469884 | 0.79 | MAPK1 (0.46) | MAPK1TSHRKDM4EMTNR1AMTNR1B | |
| SCHEMBL7594551 | 0.77 | MAPK1 (0.39) | MAPK1TSHRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23523394 | 0.75 | TSHR (0.41) | MAPK1TSHRKDM4EHIF1AMTNR1A | |
| SCHEMBL3470996 | 0.75 | TSHR (0.46) | MAPK1TSHRKDM4ECYP1A2CYP2D6 | |
| SCHEMBL3470603 | 0.75 | TSHR (0.46) | MAPK1TSHRKDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248870-B1 | OLIGO-2,6-PYRIMIDINE COMPLEXING AGENT. | NYCOMED IMAGING AS (NO) | 2001-06-19 | — | — | US | disclosed |
| US-5817774-A | Unsymmetrical complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | STERLING WINTHROP INCORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5760191-A | Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | NYCOMED IMAGING AS (NO) | 1998-06-02 | — | — | US | disclosed |
| US-5559214-A | Unsymmetrical complexing agents and targeting immunoreagents useful in thearpeutic and diagnostic compositions and methods | STERLING WINTHROP INC. (US) | 1996-09-24 | — | — | US | disclosed |