Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766667 | 0.86 | TSHR (0.41) | TSHRMAPK1CYP2C9KDM4EALDH1A1 | |
| SCHEMBL19944724 | 0.82 | KDM4E (0.49) | TSHRMAPK1CYP2C9SMN1; SMN2KDM4E | |
| SCHEMBL7774111 | 0.81 | MAPK1 (0.47) | TSHRMAPK1CYP2C9KDM4E | |
| SCHEMBL6042099 | 0.81 | CYP2C9 (0.45) | TSHRCYP2C9 | |
| SCHEMBL8050867 | 0.80 | TSHR (0.49) | TSHRMAPK1SMN1; SMN2GPBAR1CYSLTR1 | |
| SCHEMBL2063461 | 0.80 | ALDH1A1 (0.50) | TSHRMAPK1SMN1; SMN2GPBAR1CYSLTR1 | |
| SCHEMBL1135279 | 0.78 | FYN (0.56) | TSHRMAPK1SMN1; SMN2GPBAR1CYSLTR1 | |
| SCHEMBL17034727 | 0.78 | CYP2C9 (0.55) | TSHRCYP2C9ALDH1A1 | |
| SCHEMBL18175512 | 0.78 | TSHR (0.47) | TSHRMAPK1SMN1; SMN2GPBAR1CYSLTR1 | |
| SCHEMBL12100986 | 0.77 | TSHR (0.41) | TSHRMAPK1SMN1; SMN2GPBAR1CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248870-B1 | OLIGO-2,6-PYRIMIDINE COMPLEXING AGENT. | NYCOMED IMAGING AS (NO) | 2001-06-19 | — | — | US | disclosed |
| US-5817774-A | Unsymmetrical complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | STERLING WINTHROP INCORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5760191-A | Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | NYCOMED IMAGING AS (NO) | 1998-06-02 | — | — | US | disclosed |
| US-5559214-A | Unsymmetrical complexing agents and targeting immunoreagents useful in thearpeutic and diagnostic compositions and methods | STERLING WINTHROP INC. (US) | 1996-09-24 | — | — | US | disclosed |