Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | S100B | P04271 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.39 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774249 | 0.86 | MAPT (0.46) | HSD17B10ALDH1A1MAPTALOX15TDP1 | |
| SCHEMBL3881301 | 0.69 | MAPT (0.51) | HSD17B10ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL23046402 | 0.69 | MAPT (0.42) | HSD17B10ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL7774411 | 0.66 | PARP1 (0.36) | HSD17B10ALDH1A1ALOX15 | |
| SCHEMBL22740498 | 0.65 | TERT (0.44) | HSD17B10ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL22741899 | 0.65 | TERT (0.47) | HSD17B10ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL1937493 | 0.64 | HSD17B10 (0.51) | HSD17B10ERCC1DNASE1FEN1ERCC4 | |
| SCHEMBL10013171 | 0.63 | HSD17B10 (1.00) | HSD17B10ERCC1DNASE1FEN1ERCC4 | |
| SCHEMBL13701015 | 0.63 | CYP17A1 (0.43) | HSD17B10ERCC1DNASE1FEN1ERCC4 | |
| SCHEMBL11852420 | 0.62 | HSD17B10 (0.42) | HSD17B10ALDH1A1MAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294527-B1 | ANTIBIOTICS FOR METHACILLIN RESISTANT BACTERIA | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0949262-B1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KK (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-0949262-A1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-10-13 | — | — | EP | disclosed |