Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | LGMN | Q99538 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 6/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774377 | 0.86 | HSD17B10 (0.45) | MAPTSMN1; SMN2ALOX15CYP1A2CASP3 | |
| SCHEMBL7774232 | 0.80 | MAPT (0.43) | MAPTSMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL7775861 | 0.78 | MAPT (0.41) | MAPTSMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL7777231 | 0.71 | TMEM97 (0.50) | SMN1; SMN2NPC1RAB9ANPSR1 | |
| SCHEMBL31215127 | 0.69 | LRRK2 (0.43) | MAPTSMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL31006149 | 0.69 | KIF11 (0.42) | MAPTSMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL15259660 | 0.69 | KIF11 (0.42) | MAPTSMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL10347934 | 0.69 | NPC1 (0.70) | MAPTSMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL30662844 | 0.67 | HSD17B10 (0.73) | MAPTNPC1RAB9APIK3CAPIK3CD | |
| SCHEMBL1938064 | 0.67 | SLC16A3 (0.51) | MAPTNPC1RAB9APIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294527-B1 | ANTIBIOTICS FOR METHACILLIN RESISTANT BACTERIA | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0949262-B1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KK (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-0949262-A1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-10-13 | — | — | EP | disclosed |