Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HRAS | P01112 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.42 |
| ▸ | HK2 | P52789 | 1/20 | 0.42 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.42 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.42 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13491610 | 0.95 | MAPK1 (0.48) | MAPK1HRASTACR2TP53MDM2 | |
| SCHEMBL8822997 | 0.92 | MAPK1 (0.58) | MAPK1HRASLGALS3HK1HK2 | |
| SCHEMBL31134199 | 0.92 | MAPK1 (0.58) | MAPK1HRASLGALS3HK1HK2 | |
| SCHEMBL11170170 | 0.90 | MAPK1 (0.65) | MAPK1HRASTACR2LGALS3L3MBTL1 | |
| SCHEMBL1149280 | 0.89 | HRAS (0.47) | MAPK1HRASTACR2LGALS3L3MBTL1 | |
| SCHEMBL15516519 | 0.88 | TP53 (0.55) | TACR2TP53MDM2MDM4HSP90AA1 | |
| SCHEMBL12128062 | 0.88 | TACR2 (0.45) | HRASTACR2TP53MDM2LGALS3 | |
| SCHEMBL12127996 | 0.88 | TACR2 (0.45) | HRASTACR2TP53MDM2LGALS3 | |
| SCHEMBL9472134 | 0.88 | MAPK1 (0.54) | MAPK1HRASTACR2TP53MDM2 | |
| SCHEMBL6553315 | 0.86 | LGALS3 (0.47) | HRASTP53MDM2LGALS3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131311-A1 | 2-ACYLAMINO-2-DEOXY-GLUCONO-1,5-LACTONES, METHOD FOR OBTAINING SAME, COMPOSITIONS COMPRISING THEM AND USES | UNIVERSITE PIERRE ET MARIE CURIE PARIS VI (FR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000031059-A1 | 2-ACYLAMINO-2-DEOXY-GLUCONO-1,5-LACTONES, METHOD FOR OBTAINING SAME, COMPOSITIONS COMPRISING THEM AND USES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI) (FR) | 2000-06-02 | — | — | WO | disclosed |