Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HRAS | P01112 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | HK2 | P52789 | 1/20 | 0.39 |
| ▸ | MAG | P20916 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472134 | 0.92 | MAPK1 (0.54) | MAPK1HRASNOD2ALDH1A1THRB | |
| SCHEMBL7774709 | 0.90 | MAPK1 (0.50) | MAPK1HRASTACR2HK1HK2 | |
| SCHEMBL11590064 | 0.88 | MAPK1 (0.50) | MAPK1HRASNOD2ALDH1A1THRB | |
| SCHEMBL11170361 | 0.86 | MAPK1 (0.50) | MAPK1HRASNOD2POLBL3MBTL1 | |
| SCHEMBL13491610 | 0.85 | MAPK1 (0.48) | MAPK1HRASTACR2HK1HK2 | |
| SCHEMBL8822997 | 0.84 | MAPK1 (0.58) | MAPK1HRASHK1HK2MAG | |
| SCHEMBL31134199 | 0.84 | MAPK1 (0.58) | MAPK1HRASHK1HK2MAG | |
| SCHEMBL7155850 | 0.83 | MAPK1 (0.64) | MAPK1HRASALDH1A1THRBMAG | |
| SCHEMBL7155841 | 0.83 | MAPK1 (0.64) | MAPK1HRASALDH1A1THRBMAG | |
| SCHEMBL9472732 | 0.83 | MAPK1 (0.46) | MAPK1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369178-A | Glucosamine peptide derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-01-18 | — | — | US | disclosed |
| EP-0014984-B1 | GLUCOSAMINE-PEPTIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1982-12-01 | — | — | EP | disclosed |