Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775021 | 1.00 | SRD5A2 (0.50) | SRD5A2PTGER1PTGER3PTGER2TSHR | |
| SCHEMBL7770324 | 0.89 | SRD5A2 (0.55) | SRD5A2PTGER1TSHRKDM4ENPC1 | |
| SCHEMBL7770322 | 0.89 | SRD5A2 (0.55) | SRD5A2PTGER1TSHRKDM4ENPC1 | |
| SCHEMBL7774914 | 0.86 | PTGER1 (0.65) | SRD5A2PTGER1PTGER3PTGER2TSHR | |
| SCHEMBL7774912 | 0.86 | PTGER1 (0.65) | SRD5A2PTGER1PTGER3PTGER2TSHR | |
| SCHEMBL7776479 | 0.85 | PTPN1 (0.46) | PTGER1PTGER3PTGER2NPC1MEN1 | |
| SCHEMBL7776476 | 0.85 | PTPN1 (0.46) | PTGER1PTGER3PTGER2NPC1MEN1 | |
| SCHEMBL7770394 | 0.76 | ALOX15 (0.49) | SRD5A2PTGER1PTGER3PTGER2TSHR | |
| SCHEMBL7770389 | 0.76 | ALOX15 (0.49) | SRD5A2PTGER1PTGER3PTGER2TSHR | |
| SCHEMBL7774955 | 0.74 | PTPN1 (0.50) | NPC1RAB9AMEN1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809622-B1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS INC (US) | 2001-08-29 | — | — | EP | disclosed |
| US-5530157-A | NON-STEROID ANTIINFLAMMATORY DRUG | SCIOS NOVA INC. (US) | 1996-06-25 | — | — | US | disclosed |