Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | CDH1 | P12830 | 1/20 | 0.43 |
| ▸ | APC | P25054 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770322 | 1.00 | SRD5A2 (0.55) | SRD5A2ALOX15TSHRMAP4K4RXRA | |
| SCHEMBL7775021 | 0.89 | SRD5A2 (0.50) | SRD5A2ALOX15TSHRRXRARXRB | |
| SCHEMBL7775017 | 0.89 | SRD5A2 (0.50) | SRD5A2ALOX15TSHRRXRARXRB | |
| SCHEMBL7770389 | 0.86 | ALOX15 (0.49) | SRD5A2ALOX15TSHRMAP4K4RXRA | |
| SCHEMBL7770394 | 0.86 | ALOX15 (0.49) | SRD5A2ALOX15TSHRMAP4K4RXRA | |
| SCHEMBL7774951 | 0.84 | PTPN1 (0.50) | NPC1RAB9AMEN1KMT2AKCNA3 | |
| SCHEMBL7774955 | 0.84 | PTPN1 (0.50) | NPC1RAB9AMEN1KMT2AKCNA3 | |
| SCHEMBL5754075 | 0.81 | TSHR (0.74) | SRD5A2ALOX15TSHRMEN1DUSP3 | |
| SCHEMBL5754068 | 0.81 | TSHR (0.74) | SRD5A2ALOX15TSHRMEN1DUSP3 | |
| SCHEMBL7776786 | 0.76 | RXRA (0.51) | SRD5A2ALOX15TSHRRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809622-B1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS INC (US) | 2001-08-29 | — | — | EP | disclosed |
| US-5530157-A | NON-STEROID ANTIINFLAMMATORY DRUG | SCIOS NOVA INC. (US) | 1996-06-25 | — | — | US | disclosed |