Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | USP5 | P45974 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775191 | 1.00 | ESR2 (0.43) | ESR2USP5HDAC6PDE4APDE4B | |
| SCHEMBL8835221 | 0.90 | ESR2 (0.53) | ESR2USP5HDAC6PDE4APDE4B | |
| SCHEMBL8024951 | 0.88 | ESR2 (0.42) | ESR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8024950 | 0.88 | ESR2 (0.42) | ESR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17827776 | 0.88 | HTR2A (0.42) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL7779419 | 0.84 | USP5 (0.36) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL8767029 | 0.83 | USP5 (0.35) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9405321 | 0.83 | ESR2 (0.38) | ESR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8449640 | 0.83 | ESR2 (0.38) | ESR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8767567 | 0.82 | HTR2A (0.39) | USP5HDAC6HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637623-B1 | Cyclic hydrocarbon derivative and liquid crystal composition containing the same | DAINIPPON INK & CHEMICALS (JP) | 2001-10-04 | — | — | EP | disclosed |
| EP-0595144-B1 | Cyclohexyl alkenoates as components of liquid crystalline mixtures | MERCK PATENT GMBH (DE) | 1998-05-20 | — | — | EP | disclosed |
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |
| US-5536443-A | DUTERIUM CONTAINING COMPOUNDS FOOR ELECTROOPTICAL APPARATUS | DAINIPPON INK & CHEMICALS, INC. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5474707-A | Electrooptic display | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0637623-A1 | Cyclic hydrocarbon derivative and liquid crystal composition containing the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1995-02-08 | — | — | EP | disclosed |
| US-5380462-A | Cyclohexyl alkenoate compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0595144-A1 | Cyclohexyl alkenoates as components of liquid crystalline mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1994-05-04 | — | — | EP | disclosed |
| US-5185098-A | Liquid crystalline mixtures containing 3,4-difluorophenyl-substituted bicyclohexyls | HOFFMANN-LA ROCHE INC. (US) | 1993-02-09 | — | — | US | disclosed |