Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17827776 | 0.85 | HTR2A (0.42) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL7775189 | 0.84 | ESR2 (0.43) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL7775191 | 0.84 | ESR2 (0.43) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL7779441 | 0.81 | USP5 (0.35) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL8767567 | 0.80 | HTR2A (0.39) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL29389392 | 0.79 | HTR2A (0.46) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL808710 | 0.79 | HTR2A (0.46) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL23366152 | 0.78 | HTR2A (0.38) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL14525325 | 0.78 | HTR2A (0.38) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL14526618 | 0.78 | USP5 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637623-B1 | Cyclic hydrocarbon derivative and liquid crystal composition containing the same | DAINIPPON INK & CHEMICALS (JP) | 2001-10-04 | — | — | EP | disclosed |
| EP-0637623-A1 | Cyclic hydrocarbon derivative and liquid crystal composition containing the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1995-02-08 | — | — | EP | disclosed |