SCHEMBL7775236

SCHEMBL7775236

Oc1nc2ccccc2c(O)c1N=Nc1ccc(Cl)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.51
TDO2 P48775 1/20 0.51
THRB P10828 2/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
MEN1 O00255 10/20 0.41
KMT2A Q03164 10/20 0.41
MAPT P10636 10/20 0.41
L3MBTL1 Q9Y468 5/20 0.41
GAA P10253 5/20 0.41
TDP1 Q9NUW8 4/20 0.41
LMNA P02545 4/20 0.41
MMP14 P50281 2/20 0.41
CASP3 P42574 2/20 0.41
SENP7 Q9BQF6 2/20 0.41
SENP6 Q9GZR1 2/20 0.41
RECQL P46063 2/20 0.41
ALPL P05186 1/20 0.41
HSP90AA1 P07900 1/20 0.41
ALPI P09923 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11696248 0.91 THRB (0.51) IDO1THRBMEN1KMT2AMAPT
SCHEMBL11696241 0.91 THRB (0.51) IDO1THRBMEN1KMT2AMAPT
SCHEMBL15329034 0.80 POLB (0.58) THRBMEN1KMT2AMAPTGAA
SCHEMBL10488773 0.74 MEN1 (0.42) THRBMEN1KMT2AMAPTL3MBTL1
SCHEMBL10488771 0.74 MEN1 (0.42) THRBMEN1KMT2AMAPTL3MBTL1
SCHEMBL3283059 0.74 HSP90AA1 (0.55) MAOAMAOBMEN1KMT2AMAPT
SCHEMBL8430277 0.72 MAPT (0.77) IDO1TDO2THRBMEN1KMT2A
SCHEMBL8430278 0.72 MAPT (0.77) IDO1TDO2THRBMEN1KMT2A
SCHEMBL11883648 0.71 MAPT (0.36) MAOAMAOBMEN1KMT2AMAPT
SCHEMBL11883642 0.71 MAPT (0.36) MAOAMAOBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1002021-B1 DISPERSING AGENTS AND DISPERSIONS MADE THEREFROM ICI AMERICA INC (US) 2001-08-29 EP disclosed
EP-1002021-A1 DISPERSING AGENTS AND DISPERSIONS MADE THEREFROM ICI AMERICAS INC. (US) 2000-05-24 EP disclosed
WO-1999005225-A1 DISPERSING AGENTS AND DISPERSIONS MADE THEREFROM ICI AMERICAS INC. (US) 1999-02-04 WO disclosed
WO-1997041178-A1 AQUEOUS DISPERSIONS CONTAINING SUBSTITUTED SUCCINIC ANHYDRIDE DERIVATIVES ICI AMERICAS INC. (US) 1997-11-06 WO disclosed
EP-0341053-B1 Semi-polar hyperdispersants for pigment bases SUN CHEMICAL CORP (US) 1993-12-15 EP disclosed
US-4971626-A DISPERSION OF SOLID PIGMENTS FOR INKS SUN CHEMICAL CORPORATION (US) 1990-11-20 US disclosed
US-4882436-A DISPERSANTS SUN CHEMICAL CORPORATION (US) 1989-11-21 US disclosed
EP-0341053-A1 Semi-polar hyperdispersants for pigment bases SUN CHEMICAL CORPORATION (US) 1989-11-08 EP disclosed
US-4224212-A POLYALKYLENEIMINE-POLYESTERS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-09-23 US disclosed