Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735817 | 1.00 | TRHR (0.53) | TRHR | |
| SCHEMBL11047961 | 1.00 | TRHR (0.53) | TRHR | |
| SCHEMBL11762284 | 0.89 | TRHR (0.52) | TRHR | |
| SCHEMBL11762294 | 0.89 | TRHR (0.52) | TRHR | |
| SCHEMBL10345484 | 0.87 | TRHR (0.55) | TRHR | |
| SCHEMBL7334062 | 0.86 | TRHR (0.56) | TRHR | |
| SCHEMBL7326652 | 0.86 | TRHR (0.56) | TRHR | |
| SCHEMBL7334219 | 0.86 | TRHR (0.55) | TRHR | |
| SCHEMBL9745345 | 0.85 | TRHR (0.59) | TRHR | |
| SCHEMBL7329695 | 0.84 | TRHR (0.54) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426378-A | Thyrotropin releasing hormone in therapy of shock and as a central nervous system stimulant | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1984-01-17 | — | — | US | claimed |
| US-4112073-A | Medicinal composition comprising adrenal cortical hormone and thyroid stimulating hormone releasing hormone | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-09-05 | — | — | US | claimed |
| EP-1117425-A2 | METHODS FOR THE TREATMENT OF NON-THYROID DISORDERS | CELTRIX PHARMACEUTICALS, INC. (US) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020024-A2 | METHODS FOR THE TREATMENT OF NON-THYROID DISORDERS | CELTRIX PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |
| US-4442090-A | ACYLATED AMINO ACID | KYOTO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1984-04-10 | — | — | US | disclosed |
| US-4426378-A | Thyrotropin releasing hormone in therapy of shock and as a central nervous system stimulant | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1984-01-17 | — | — | US | disclosed |
| US-4150120-A | Ophthalmic | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-17 | — | — | US | disclosed |
| US-4112073-A | Medicinal composition comprising adrenal cortical hormone and thyroid stimulating hormone releasing hormone | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-09-05 | — | — | US | disclosed |