Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334062 | 0.93 | TRHR (0.56) | TRHR | |
| SCHEMBL7326652 | 0.93 | TRHR (0.56) | TRHR | |
| Protirelin SCHEMBL8364920 | 0.88 | TRHR (0.71) | TRHR | |
| Protirelin SCHEMBL20659679 | 0.88 | TRHR (0.71) | TRHR | |
| Protirelin SCHEMBL11798811 | 0.88 | TRHR (0.71) | TRHR | |
| Protirelin SCHEMBL14280929 | 0.88 | TRHR (0.71) | TRHR | |
| Protirelin SCHEMBL2182035 | 0.88 | TRHR (0.71) | TRHR | |
| SCHEMBL10345484 | 0.87 | TRHR (0.55) | TRHR | |
| SCHEMBL7334633 | 0.87 | TRHR (0.55) | TRHR | |
| SCHEMBL7334219 | 0.86 | TRHR (0.55) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |