Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.59 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | GALR3 | O60755 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11786436 | 1.00 | EEF2K (0.59) | EEF2KCCR5MEN1KMT2AHTT | |
| SCHEMBL7776941 | 0.98 | EEF2K (0.61) | EEF2KCCR5MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL11783365 | 0.91 | EEF2K (0.51) | EEF2KMEN1KMT2AHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11784271 | 0.83 | EEF2K (0.43) | EEF2KCCR5HTT | |
| Hydrochloric Acid SCHEMBL7216909 | 0.82 | EEF2K (0.45) | EEF2KCCR5MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL7773825 | 0.82 | EEF2K (0.45) | EEF2KCCR5MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL11779798 | 0.82 | EEF2K (0.45) | EEF2KCCR5MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL31093206 | 0.82 | EEF2K (0.45) | EEF2KCCR5MEN1KMT2AHTT | |
| SCHEMBL24052262 | 0.80 | EEF2K (0.46) | EEF2KMEN1KMT2AHTTGBA1 | |
| SCHEMBL31093210 | 0.80 | EEF2K (0.46) | EEF2KMEN1KMT2AHTTGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877298-B1 | Coated xerographic photographic paper | XEROX CORP (US) | 2001-08-29 | — | — | EP | claimed |
| US-5846637-A | Coated xerographic photographic paper | XEROX CORPORATION (US) | 1998-12-08 | — | — | US | claimed |
| EP-0877298-A2 | Coated xerographic photographic paper | Xerox Corporation (US) | 1998-11-11 | — | — | EP | claimed |
| US-6210816-B1 | Translucent xerographic recording substrates | XEROX CORPORATION | 2001-04-03 | — | — | US | disclosed |
| US-6171702-B1 | Coated substrates | XEROX CORPORATION | 2001-01-09 | — | — | US | disclosed |
| US-6096443-A | Transparencies | XEROX CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| US-5846637-A | Coated xerographic photographic paper | XEROX CORPORATION (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0877298-A2 | Coated xerographic photographic paper | Xerox Corporation (US) | 1998-11-11 | — | — | EP | disclosed |