Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11781058 | 0.87 | EEF2K (0.39) | EEF2KCCR5MEN1KMT2ASPHK1 | |
| SCHEMBL17765553 | 0.85 | EEF2K (0.38) | EEF2KMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11253281 | 0.84 | EEF2K (0.37) | EEF2KCCR5MEN1KMT2ASPHK1 | |
| Hydrochloric Acid SCHEMBL7775450 | 0.82 | EEF2K (0.59) | EEF2KCCR5MEN1KMT2AGBA1 | |
| Hydrochloric Acid SCHEMBL11786436 | 0.82 | EEF2K (0.59) | EEF2KCCR5MEN1KMT2AGBA1 | |
| Hydrochloric Acid SCHEMBL31093206 | 0.81 | EEF2K (0.45) | EEF2KCCR5MEN1KMT2AGBA1 | |
| Hydrochloric Acid SCHEMBL7773825 | 0.81 | EEF2K (0.45) | EEF2KCCR5MEN1KMT2AGBA1 | |
| Hydrochloric Acid SCHEMBL7216909 | 0.81 | EEF2K (0.45) | EEF2KCCR5MEN1KMT2AGBA1 | |
| SCHEMBL7776941 | 0.80 | EEF2K (0.61) | EEF2KCCR5MEN1KMT2AGBA1 | |
| SCHEMBL24052262 | 0.79 | EEF2K (0.46) | EEF2KMEN1KMT2AGBA1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931129-A | FLUOROELASTOMER COMPOSITION | DAIKIN KOGYO CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |