Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | ACR | P10323 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770715 | 0.91 | NPC1 (0.51) | NPC1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL7775414 | 0.90 | NPC1 (0.52) | NPC1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL7776932 | 0.90 | NPC1 (0.52) | NPC1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL8026374 | 0.87 | NPC1 (0.52) | NPC1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL7619158 | 0.87 | NPC1 (0.52) | NPC1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL28513661 | 0.87 | NPC1 (0.49) | NPC1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL7777073 | 0.86 | ADRB2 (0.44) | NPC1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL7775472 | 0.86 | ADRB2 (0.44) | NPC1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL8021884 | 0.86 | ADRB2 (0.44) | NPC1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL8962712 | 0.86 | LMNA (0.60) | NPC1MAPTRAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985721-B1 | Nematic liquid crystalline organosiloxanes crosslinkable to optical anisotropic polymer layers | CONSORTIUM ELEKTROCHEM IND (DE) | 2001-08-29 | — | — | EP | disclosed |
| EP-0985721-A1 | Nematic liquid crystalline organosiloxanes crosslinkable to optical anisotropic polymer layers | Consortium für elektrochemische Industrie GmbH (DE) | 2000-03-15 | — | — | EP | disclosed |