Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767872 | 0.90 | KAT2B (0.46) | MGLLSMN1; SMN2KDM4EKAT2BMAPT | |
| SCHEMBL7772069 | 0.89 | KDM4E (0.45) | SMN1; SMN2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL7772066 | 0.84 | SMN1; SMN2 (0.44) | MGLLSMN1; SMN2KDM4EKAT2BNPC1 | |
| SCHEMBL7775651 | 0.81 | LPAR1 (0.40) | SMN1; SMN2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL7773564 | 0.76 | KDM4E (0.47) | SMN1; SMN2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL7772059 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EMAPTALDH1A1TSHR | |
| SCHEMBL7772041 | 0.72 | KAT2B (0.47) | MGLLSMN1; SMN2KDM4EKAT2BNPC1 | |
| SCHEMBL8645287 | 0.70 | ELANE (0.52) | MGLLSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7772048 | 0.70 | F2 (0.43) | SMN1; SMN2KDM4EKAT2BNPC1RAB9A | |
| SCHEMBL7773577 | 0.70 | KAT2B (0.47) | SMN1; SMN2KDM4EKAT2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |