Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767872 | 0.91 | KAT2B (0.46) | KDM4ESMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL7775656 | 0.89 | MGLL (0.40) | KDM4ESMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL7775651 | 0.89 | LPAR1 (0.40) | KDM4ESMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL7773564 | 0.84 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL7772066 | 0.82 | SMN1; SMN2 (0.44) | KDM4ESMN1; SMN2ALDH1A1TSHRCYP1A2 | |
| SCHEMBL7772059 | 0.80 | SMN1; SMN2 (0.43) | KDM4ESMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL8108980 | 0.71 | PTGDR2 (0.45) | KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL7772041 | 0.70 | KAT2B (0.47) | KDM4ESMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL7773817 | 0.70 | F2 (0.45) | KDM4EALDH1A1MAPTHPGDRXFP1 | |
| SCHEMBL7772048 | 0.69 | F2 (0.43) | KDM4ESMN1; SMN2ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |