Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773564 | 0.82 | KDM4E (0.47) | SMN1; SMN2KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL7772069 | 0.80 | KDM4E (0.45) | SMN1; SMN2KDM4EMAPTALDH1A1POLB | |
| SCHEMBL7773566 | 0.80 | MAPT (0.44) | SMN1; SMN2KDM4EHTTMAPTALDH1A1 | |
| SCHEMBL7771927 | 0.79 | KDM4E (0.44) | SMN1; SMN2KDM4EHTTMAPTALDH1A1 | |
| SCHEMBL7773563 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EHTTMAPTALDH1A1 | |
| SCHEMBL7772045 | 0.77 | F2 (0.44) | SMN1; SMN2KDM4EHTTMAPTALDH1A1 | |
| SCHEMBL7767872 | 0.74 | KAT2B (0.46) | SMN1; SMN2KDM4EHTTMAPTALDH1A1 | |
| SCHEMBL7772056 | 0.74 | PDE4B (0.41) | SMN1; SMN2KDM4EHTTMAPTALDH1A1 | |
| SCHEMBL7775656 | 0.73 | MGLL (0.40) | SMN1; SMN2KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL7775651 | 0.73 | LPAR1 (0.40) | SMN1; SMN2KDM4EMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |