Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL9560447 | 0.89 | TSHR (0.62) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL9047549 | 0.84 | TSHR (0.40) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL2486521 | 0.84 | TSHR (0.56) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL7287852 | 0.84 | TSHR (0.60) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL11454239 | 0.84 | TSHR (0.60) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL7775660 | 0.84 | ALDH1A1 (0.38) | TSHRMAPK1MEN1KMT2AHTT | |
| SCHEMBL8257768 | 0.82 | TSHR (0.64) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL11466912 | 0.82 | MEN1 (0.57) | TSHRMAPK1MEN1KMT2ATHRB | |
| Butoxyethanol SCHEMBL9778151 | 0.82 | TSHR (0.71) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL31441415 | 0.82 | TSHR (0.53) | TSHRMAPK1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115259736-B | Halogen-free quaternary amines and their use | 亨斯迈石油化学有限责任公司 | 2024-05-07 | — | — | CN | disclosed |
| EP-3481787-B1 | HALOGEN-FREE QUATERNARY AMINIES AND USES THEREOF | HUNTSMAN PETROCHEMICAL LLC (US) | 2024-02-28 | — | — | EP | disclosed |
| US-11542199-B2 | Halogen-free quaternary amines and uses thereof | HUNTSMAN PETROCHEMICAL LLC (US) | 2023-01-03 | — | — | US | disclosed |
| CN-115259736-A | Halogen-free quaternary amines and their use | 亨斯迈石油化学有限责任公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-108698927-B | Halogen-free quaternary amines and their use | 亨斯迈石油化学有限责任公司 | 2022-08-09 | — | — | CN | disclosed |
| US-20190112229-A1 | HALOGEN-FREE QUATERNARY AMINES AND USES THEREOF | HUNTSMAN PETROCHEMICAL LLC | 2019-04-18 | — | — | US | disclosed |
| EP-0733045-B1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | EP | disclosed |
| US-5880130-A | TREATMENT OF CELL-PROLIFERATION DISEASES | ZENECA LIMITED (GB) | 1999-03-09 | — | — | US | disclosed |
| EP-0733045-A1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015952-A1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ZENECA LIMITED (GB) | 1995-06-15 | — | — | WO | disclosed |