Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | OGT | O15294 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133118 | 0.89 | TSHR (0.60) | TSHREPHX1MEN1TP53CYP1A2 | |
| SCHEMBL16108678 | 0.84 | TSHR (0.53) | TSHREPHX1MEN1TP53CYP1A2 | |
| SCHEMBL14966864 | 0.84 | TSHR (0.56) | TSHREPHX1MEN1TP53CYP1A2 | |
| SCHEMBL7777512 | 0.84 | TSHR (0.46) | TSHRSLC6A3EPHX1MEN1KMT2A | |
| SCHEMBL9525910 | 0.80 | TSHR (0.46) | TSHRSLC6A4SLC6A3EPHX1MEN1 | |
| SCHEMBL9692696 | 0.79 | TSHR (0.49) | TSHRSLC6A4SLC6A3MEN1HPGD | |
| SCHEMBL7776121 | 0.78 | ALDH1A1 (0.40) | TSHREPHX1MEN1CYP1A2CYP2C9 | |
| SCHEMBL6070420 | 0.78 | EPHX1 (0.48) | TSHREPHX1MEN1TP53CYP1A2 | |
| SCHEMBL6069547 | 0.78 | EPHX1 (0.48) | TSHREPHX1MEN1TP53CYP1A2 | |
| SCHEMBL9264620 | 0.78 | EPHX1 (0.48) | TSHREPHX1MEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127885-A2 | Optically active epoxypropionate derivatives, intermediates, and processes for their production | Tosoh Corporation (JP) | 2001-08-29 | — | — | EP | disclosed |