Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | FABP7 | O15540 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692787 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDHSD17B10GAA | |
| SCHEMBL28943320 | 0.80 | PTGS2 (0.46) | ALDH1A1HPGDHSD17B10GAAKDM4E | |
| SCHEMBL9133118 | 0.78 | TSHR (0.60) | ALDH1A1ELANETSHRHPGDHSD17B10 | |
| SCHEMBL28638160 | 0.78 | PTGS2 (0.44) | ALDH1A1TSHRHPGDHSD17B10GAA | |
| SCHEMBL7775672 | 0.78 | TSHR (0.49) | ALDH1A1TSHRHPGDEPHX1CYP1A2 | |
| SCHEMBL3834445 | 0.76 | EPHX1 (0.62) | ALDH1A1HPGDKDM4EMAPTPTGS2 | |
| SCHEMBL3834443 | 0.76 | EPHX1 (0.62) | ALDH1A1HPGDKDM4EMAPTPTGS2 | |
| SCHEMBL3834446 | 0.76 | EPHX1 (0.62) | ALDH1A1HPGDKDM4EMAPTPTGS2 | |
| SCHEMBL7777512 | 0.75 | TSHR (0.46) | ALDH1A1TSHRGAAEPHX1FABP7 | |
| SCHEMBL16639436 | 0.73 | ALDH1A1 (0.46) | ALDH1A1ELANETSHRHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127885-A2 | Optically active epoxypropionate derivatives, intermediates, and processes for their production | Tosoh Corporation (JP) | 2001-08-29 | — | — | EP | disclosed |