SCHEMBL7775801

SCHEMBL7775801

Nc1ccc(-c2c(-c3ccccc3)cc(N)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.52
TAAR1 Q96RJ0 2/20 0.52
CYP3A4 P08684 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ALDH1A1 P00352 6/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
MAPT P10636 4/20 0.43
HPGD P15428 4/20 0.43
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
KDM4E B2RXH2 3/20 0.39
GLA P06280 2/20 0.39
ALOX15 P16050 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21280056 0.92 HSD17B10 (0.50) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL20115053 0.90 HSD17B10 (0.58) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL4349114 0.90 HSD17B10 (0.58) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL7183903 0.90 HSD17B10 (0.58) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
Ammonia Solution, Strong SCHEMBL9664673 0.88 HSD17B10 (0.56) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL10707335 0.84 HSD17B10 (0.47) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL9550986 0.82 HSD17B10 (0.54) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL38925 0.82 HSD17B10 (0.54) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL651427 0.82 HSD17B10 (0.54) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL6836070 0.81 ALDH1A1 (0.50) HSD17B10TAAR1CYP3A4TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115348985-A Method for adjusting the electron energy level of a covalent organic framework for the manufacture of high-rate sodium-ion battery anodes 印度科学教育研究院 2022-11-15 CN claimed
JP-8099941-A None JP disclosed
US-12091612-B2 Electrochromic element RICOH COMPANY, LTD. (JP) 2024-09-17 US disclosed
CN-111484478-B Preparation method and application of linear C2 symmetrical compound and lanthanide polynuclear complex thereof 中国科学院福建物质结构研究所 2022-12-06 CN disclosed
CN-115348985-A Method for adjusting the electron energy level of a covalent organic framework for the manufacture of high-rate sodium-ion battery anodes 印度科学教育研究院 2022-11-15 CN disclosed
CN-113929585-A Organic compound and organic electroluminescent device 北京鼎材科技有限公司 2022-01-14 CN disclosed
CN-113929646-A Organic compound and organic electroluminescent device 北京鼎材科技有限公司 2022-01-14 CN disclosed
EP-3889130-A1 ELECTROCHROMIC ELEMENT Ricoh Company, Ltd. (JP) 2021-10-06 EP disclosed
CN-113467146-A Electrochromic element 株式会社理光 2021-10-01 CN disclosed
US-20210301197-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2021-09-30 US disclosed
EP-2671271-A1 PHOTOVOLTAIC ELEMENT BASF SE (DE) 2013-12-11 EP disclosed
WO-2012104742-A1 PHOTOVOLTAIC ELEMENT BASF SE (DE) 2012-08-09 WO disclosed
JP-2001181240-A METHOD FOR PRODUCING BENZIDINE COMPOUND HODOGAYA CHEM CO LTD 2001-07-03 JP disclosed
EP-0650955-B1 Amine compound and electro-luminescence device comprising same HODOGAYA CHEMICAL CO LTD (JP) 1998-08-19 EP disclosed
US-5707747-A CHARGE TRANSPORT COMPOUNDS HODOGAYA CHEMICAL CO., LTD. (JP) 1998-01-13 US disclosed
US-5639914-A DURABLE, STABLE, LOW VOLTAGE ELECTROLUMINESCENT EMITTERS HODOGAYA CHEMICAL CO., LTD. (JP) 1997-06-17 US disclosed
US-5585212-A LAYER HAVING BLEND OF HIGHER AND LOWER MOLECULAR WEIGHT POLYCARBONATES WITH CHARGE GENERATING AND CHARGE TRANSPORTING MATERIALS, SENSITIVITY, DURABILITY, STRENGTH, EASE OF MANUFACTURE MINOLTA CO., LTD. (JP) 1996-12-17 US disclosed
JP-H0899941-A AMINE COMPOUND HODOGAYA CHEM CO LTD 1996-04-16 JP disclosed
EP-0650955-A1 Amine compound and electro-luminescence device comprising same HODOGAYA CHEMICAL CO., LTD. (JP) 1995-05-03 EP disclosed