Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29596767 | 0.82 | HSD17B10 (0.48) | ALDH1A1HSD17B10CYP3A4TAAR1TDP1 | |
| SCHEMBL904510 | 0.82 | HSD17B10 (0.48) | ALDH1A1HSD17B10CYP3A4TAAR1TDP1 | |
| SCHEMBL7775801 | 0.81 | HSD17B10 (0.52) | ALDH1A1HSD17B10CYP3A4TAAR1TDP1 | |
| SCHEMBL1901150 | 0.77 | PDE4A (0.42) | ALDH1A1HSD17B10TDP1HPGDMEN1 | |
| Biphenyl-4-Amine SCHEMBL6081432 | 0.77 | ALDH1A1 (0.77) | ALDH1A1HSD17B10CYP3A4TAAR1TDP1 | |
| Benzidine SCHEMBL28123514 | 0.77 | ALDH1A1 (0.77) | ALDH1A1HSD17B10CYP3A4TAAR1TDP1 | |
| SCHEMBL8430179 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CYP3A4TAAR1TDP1 | |
| SCHEMBL3174480 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CYP3A4TAAR1TDP1 | |
| SCHEMBL20115053 | 0.75 | HSD17B10 (0.58) | ALDH1A1HSD17B10CYP3A4TAAR1TDP1 | |
| SCHEMBL28991791 | 0.75 | ALDH1A1 (0.74) | ALDH1A1HSD17B10CYP3A4TAAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753363-B1 | BASIC NITROGEN-CONTAINING COMPOUND, PHOSPHORUS COMPOUND FLAME RETARDANT, AND AROMATIC COMPOUND ACCELERATOR; MOLDABILITY | POLYPLASTICS CO., LTD. (JP) | 2004-06-22 | — | — | US | disclosed |