Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774088 | 0.80 | ALDH1A1 (0.39) | PKMLIG1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7774397 | 0.76 | HSD17B10 (0.36) | STSPKMLIG1SMN1; SMN2LMNA | |
| SCHEMBL204515 | 0.74 | KDM4E (0.48) | NPC1RAB9ASMN1; SMN2TBXAS1KDM4E | |
| SCHEMBL30414903 | 0.74 | KDM4E (0.48) | NPC1RAB9ASMN1; SMN2TBXAS1KDM4E | |
| SCHEMBL7769690 | 0.74 | TSHR (0.48) | NPC1RAB9ASMN1; SMN2KDM4ETDP1 | |
| SCHEMBL28456554 | 0.73 | TTR (0.49) | NPC1RAB9ASMN1; SMN2TBXAS1KDM4E | |
| SCHEMBL30414825 | 0.71 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2TBXAS1KDM4E | |
| SCHEMBL2486863 | 0.71 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2TBXAS1KDM4E | |
| SCHEMBL28456827 | 0.68 | STS (0.45) | STSNPC1RAB9ASMN1; SMN2TBXAS1 | |
| SCHEMBL11249253 | 0.67 | CYP1A2 (0.54) | NPC1RAB9ASMN1; SMN2KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294527-B1 | ANTIBIOTICS FOR METHACILLIN RESISTANT BACTERIA | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0949262-B1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KK (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-0949262-A1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-10-13 | — | — | EP | disclosed |