Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774088 | 0.80 | ALDH1A1 (0.39) | HSD17B10CA2ALDH1A1ALOX15GAA | |
| SCHEMBL7774018 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2MIFHTT | |
| SCHEMBL7774411 | 0.76 | PARP1 (0.36) | HSD17B10PARP1STSCA2APP | |
| SCHEMBL7775951 | 0.76 | STS (0.41) | PARP1STSALDH1A1LMNAGAA | |
| SCHEMBL7769690 | 0.74 | TSHR (0.48) | HSD17B10ALDH1A1ALOX15LMNAGAA | |
| SCHEMBL7777262 | 0.73 | MAPT (0.43) | HSD17B10PARP1MIFCA12CA9 | |
| SCHEMBL9016603 | 0.72 | GPR35 (0.41) | HSD17B10ALDH1A1ALOX15HPGDHTT | |
| SCHEMBL13520159 | 0.69 | LIMK1 (0.44) | HSD17B10PARP1CA2APPMIF | |
| SCHEMBL7774232 | 0.67 | MAPT (0.43) | ALDH1A1ALOX15GAASMN1; SMN2PKM | |
| SCHEMBL19155499 | 0.66 | LIMK1 (0.42) | HSD17B10PARP1CA2APPMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294527-B1 | ANTIBIOTICS FOR METHACILLIN RESISTANT BACTERIA | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0949262-B1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KK (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-0949262-A1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-10-13 | — | — | EP | disclosed |