SCHEMBL7776164

SCHEMBL7776164

O=C(Nc1ccccc1)Nc1ccc(S(=O)(=O)NC(=O)c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 1/20 0.64
FLT4 P35916 1/20 0.64
KDR P35968 1/20 0.64
MEN1 O00255 5/20 0.60
KMT2A Q03164 5/20 0.60
POLB P06746 2/20 0.60
NPC1 O15118 2/20 0.60
MITF O75030 1/20 0.60
RAB9A P51151 1/20 0.60
CA2 P00918 2/20 0.58
CA9 Q16790 2/20 0.58
CA1 P00915 1/20 0.58
GAA P10253 3/20 0.57
MMP9 P14780 3/20 0.56
LMNA P02545 1/20 0.56
MAPT P10636 1/20 0.56
MAPK1 P28482 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CA12 O43570 1/20 0.55
MMP1 P03956 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7776322 1.00 FLT1 (0.64) FLT1FLT4KDRMEN1KMT2A
SCHEMBL8658616 0.90 KDR (0.62) FLT1FLT4KDRMEN1KMT2A
SCHEMBL7774805 0.89 FLT1 (0.63) FLT1FLT4KDRMEN1KMT2A
SCHEMBL8768067 0.89 FLT1 (0.57) FLT1FLT4KDRMEN1KMT2A
SCHEMBL8654939 0.88 FLT1 (0.76) FLT1FLT4KDRMEN1KMT2A
SCHEMBL9468106 0.88 FLT1 (0.64) FLT1FLT4KDRMEN1KMT2A
SCHEMBL6295620 0.87 MEN1 (0.65) FLT1FLT4KDRMEN1KMT2A
SCHEMBL8661710 0.87 FLT1 (0.74) FLT1FLT4KDRMEN1KMT2A
SCHEMBL6295675 0.87 SIRT1 (0.60) FLT1FLT4KDRMEN1KMT2A
SCHEMBL23909567 0.85 FLT1 (0.85) FLT1FLT4KDRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed
EP-0699662-B1 Novel urea (thiourea) derivative and thermal recording sheet using same JUJO PAPER CO LTD (JP) 1998-10-21 EP disclosed
US-5661100-A HAVING HIGH SENSITIVITY, SUPERIOR THERMAL RESISTANCE, WATER RESISTANCE, OIL RESISTANCE NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-26 US disclosed
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed
EP-0699662-A1 Novel urea (thiourea) derivative and thermal recording sheet using same NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-03-06 EP disclosed