SCHEMBL7776295

SCHEMBL7776295

S=C1C=CCC2CC=CC=C12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8608379 0.73 MAOA (0.33)
SCHEMBL7777743 0.69
SCHEMBL6487916 0.68 MAOA (0.31)
SCHEMBL4220822 0.67
SCHEMBL9472575 0.66
SCHEMBL3809774 0.65
SCHEMBL1078392 0.64
SCHEMBL11563490 0.62
SCHEMBL12488069 0.62
SCHEMBL9278390 0.61 POLB (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0759903-B1 PROCESS FOR THE PREPARATION OF BENZOPHENTHIONES AND BENZOPHENONES AVECIA LTD (GB) 2001-09-05 EP claimed
US-5777172-A Process for the preparation of benzophenthiones and benzophenones ZENECA LIMITED (GB) 1998-07-07 US claimed
EP-0759903-A1 PROCESS FOR THE PREPARATION OF BENZOPHENTHIONES AND BENZOPHENONES ZENECA LIMITED (GB) 1997-03-05 EP claimed
WO-1995031435-A1 PROCESS FOR THE PREPARATION OF BENZOPHENTHIONES AND BENZOPHENONES ZENECA LIMITED (GB) 1995-11-23 WO claimed
EP-0759903-B1 PROCESS FOR THE PREPARATION OF BENZOPHENTHIONES AND BENZOPHENONES AVECIA LTD (GB) 2001-09-05 EP disclosed
EP-0759903-B1 PROCESS FOR THE PREPARATION OF BENZOPHENTHIONES AND BENZOPHENONES AVECIA LTD (GB) 2001-09-05 EP disclosed
US-5777172-A Process for the preparation of benzophenthiones and benzophenones ZENECA LIMITED (GB) 1998-07-07 US disclosed
US-5777172-A Process for the preparation of benzophenthiones and benzophenones ZENECA LIMITED (GB) 1998-07-07 US disclosed
US-5777172-A Process for the preparation of benzophenthiones and benzophenones ZENECA LIMITED (GB) 1998-07-07 US disclosed
EP-0759903-A1 PROCESS FOR THE PREPARATION OF BENZOPHENTHIONES AND BENZOPHENONES ZENECA LIMITED (GB) 1997-03-05 EP disclosed
EP-0759903-A1 PROCESS FOR THE PREPARATION OF BENZOPHENTHIONES AND BENZOPHENONES ZENECA LIMITED (GB) 1997-03-05 EP disclosed
WO-1995031435-A1 PROCESS FOR THE PREPARATION OF BENZOPHENTHIONES AND BENZOPHENONES ZENECA LIMITED (GB) 1995-11-23 WO disclosed
WO-1995031435-A1 PROCESS FOR THE PREPARATION OF BENZOPHENTHIONES AND BENZOPHENONES ZENECA LIMITED (GB) 1995-11-23 WO disclosed