⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67711 | 0.78 | — | — | |
| SCHEMBL1159919 | 0.78 | — | — | |
| SCHEMBL312465 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL27634057 | 0.71 | — | — | |
| Piperazine SCHEMBL27718655 | 0.68 | SLC18A3 (0.31) | — | |
| SCHEMBL7776295 | 0.66 | — | — | |
| SCHEMBL12488069 | 0.64 | — | — | |
| SCHEMBL27526976 | 0.63 | MAPT (0.30) | — | |
| SCHEMBL30239906 | 0.62 | — | — | |
| SCHEMBL8831837 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575749-A2 | Use of potassium-channel activators for the manufacture of a medicament for the treatment of gastrointertinal ulcers | E.R. SQUIBB & SONS, INC. (US) | 1993-12-29 | — | — | EP | claimed |
| US-5262419-A | Antiulcer agents | E. R. SQUIBB & SONS, INC. (US) | 1993-11-16 | — | — | US | claimed |
| EP-0250077-B1 | PHARMACOLOGICALLY ACTIVE BENZOPYRANES | BEECHAM GROUP PLC (GB) | 1992-01-02 | — | — | EP | claimed |
| EP-0205292-B1 | Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1991-11-06 | — | — | EP | claimed |
| EP-0250077-A2 | Pharmacologically active benzopyranes | BEECHAM GROUP PLC (GB) | 1987-12-23 | — | — | EP | claimed |
| WO-1987007607-A1 | PYRANO (3,2-c) PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP P.L.C. (GB) | 1987-12-17 | — | — | WO | claimed |
| EP-0575749-A2 | Use of potassium-channel activators for the manufacture of a medicament for the treatment of gastrointertinal ulcers | E.R. SQUIBB & SONS, INC. (US) | 1993-12-29 | — | — | EP | disclosed |
| US-5262419-A | Antiulcer agents | E. R. SQUIBB & SONS, INC. (US) | 1993-11-16 | — | — | US | disclosed |
| US-5210234-A | Benzopyran intermediates | BEECHAM GROUP P.L.C. (GB) | 1993-05-11 | — | — | US | disclosed |
| EP-0516658-A1 | BENZOPYRANS HAVING PHARMACOLOGICAL ACTIVITY | BEECHAM GROUP PLC (GB) | 1992-12-09 | — | — | EP | disclosed |
| EP-0465583-A1 | USE OF A POTASSIC AGONIST IN THE TREATMENT OF GLAUCOMA | ELF SANOFI (FR) | 1992-01-15 | — | — | EP | disclosed |
| EP-0250077-B1 | PHARMACOLOGICALLY ACTIVE BENZOPYRANES | BEECHAM GROUP PLC (GB) | 1992-01-02 | — | — | EP | disclosed |
| US-5075460-A | Hypotensive agents | BEECHAM GROUP PLC (GB) | 1991-12-24 | — | — | US | disclosed |
| WO-1991011446-A1 | BENZOPYRANS HAVING PHARMACOLOGICAL ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-08-08 | — | — | WO | disclosed |
| WO-1990011758-A2 | USE OF A POTASSIC AGONIST IN THE TREATMENT OF GLAUCOMA | SANOFI (FR) | 1990-10-18 | — | — | WO | disclosed |
| US-4943582-A | Active compounds | BEECHAM GROUP P.L.C. (GB) | 1990-07-24 | — | — | US | disclosed |
| US-4904784-A | Active compounds | BEECHAM GROUP P.L.C. (GB) | 1990-02-27 | — | — | US | disclosed |
| US-4812459-A | PYRANOPYRIDINES | BEECHAM GROUP P.L.C. (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0250077-A2 | Pharmacologically active benzopyranes | BEECHAM GROUP PLC (GB) | 1987-12-23 | — | — | EP | disclosed |
| WO-1987007607-A1 | PYRANO (3,2-c) PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP P.L.C. (GB) | 1987-12-17 | — | — | WO | disclosed |