Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684521 | 1.00 | TRPA1 (0.56) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL29953635 | 0.80 | TRPA1 (0.56) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL2823017 | 0.80 | TRPA1 (0.56) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL7776307 | 0.79 | TRPA1 (0.41) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL7776310 | 0.78 | TRPA1 (0.43) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL42414 | 0.77 | TDP1 (0.50) | TRPA1TP53TDP1ALOX15HSD17B10 | |
| SCHEMBL3791591 | 0.77 | TYR (0.42) | TP53TDP1LMNAALOX15HSD17B10 | |
| SCHEMBL30381231 | 0.77 | TYR (0.42) | TP53TDP1LMNAALOX15HSD17B10 | |
| SCHEMBL29591086 | 0.77 | TDP1 (0.50) | TRPA1TP53TDP1ALOX15HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28219158 | 0.75 | TDP1 (0.48) | TRPA1TP53TDP1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119573-A2 | BIPYRIDINE MANGANESE COMPLEXES | EUKARION, INC. (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000009512-A2 | BIPYRIDINE MANGANESE COMPLEXES | EUKARION, INC. (US) | 2000-02-24 | — | — | WO | disclosed |