Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776306 | 0.79 | TRPA1 (0.56) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL1684521 | 0.79 | TRPA1 (0.56) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL7776310 | 0.75 | TRPA1 (0.43) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL1228414 | 0.74 | ACHE (0.58) | ACHEALDH1A1GAAMAPTKMT2A | |
| SCHEMBL29955197 | 0.74 | ACHE (0.58) | ACHEALDH1A1GAAMAPTKMT2A | |
| SCHEMBL7478722 | 0.71 | ADORA3 (0.40) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL2140990 | 0.69 | MAPT (0.45) | TDP1LMNAACHEALDH1A1GAA | |
| SCHEMBL29551713 | 0.68 | TRPA1 (0.48) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL31114558 | 0.68 | TRPA1 (0.48) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL29952684 | 0.68 | GPR3 (0.39) | TDP1CHRM1ADRA1AHTR2BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119573-A2 | BIPYRIDINE MANGANESE COMPLEXES | EUKARION, INC. (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000009512-A2 | BIPYRIDINE MANGANESE COMPLEXES | EUKARION, INC. (US) | 2000-02-24 | — | — | WO | disclosed |