Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980070 | 0.81 | ERN1 (0.47) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL7232450 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL7776329 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL30274968 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL7776334 | 0.75 | KDM4E (0.37) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL7768718 | 0.70 | ALDH1A1 (0.46) | KDM4EALDH1A1LMNA | |
| SCHEMBL36529 | 0.67 | ALDH1A1 (0.65) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL27800318 | 0.67 | ALDH1A1 (0.65) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL7776321 | 0.67 | — | — | |
| SCHEMBL7776310 | 0.67 | TRPA1 (0.43) | ALDH1A1LMNAGAAMAPTSELL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119573-A2 | BIPYRIDINE MANGANESE COMPLEXES | EUKARION, INC. (US) | 2001-08-01 | — | — | EP | disclosed |
| US-6177419-B1 | ANTIOXIDANT CHELATE COMPOUNDS FOR PREVENTING OXYGEN FREE RADICAL-ASSOCIATED DISEASES IN MAMMALS; NEUROPROTECTANTS, SUPEROXIDE DISMUTASE (SOD), CATALASE (CAT) AND/OR PEROXIDASE (POD) MIMETICS | EUKARION, INC. | 2001-01-23 | — | — | US | disclosed |
| WO-2000009512-A2 | BIPYRIDINE MANGANESE COMPLEXES | EUKARION, INC. (US) | 2000-02-24 | — | — | WO | disclosed |