Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11646902 | 0.90 | MAPT (0.50) | MAPTLMNASERPINA6CYP3A4MEN1 | |
| SCHEMBL16741271 | 0.84 | SERPINA6 (0.67) | MAPTLMNASERPINA6CYP3A4MEN1 | |
| SCHEMBL3225293 | 0.82 | SHBG (0.65) | MAPTLMNASERPINA6CYP3A4MAPK1 | |
| SCHEMBL5550822 | 0.82 | SHBG (0.65) | MAPTLMNASERPINA6CYP3A4MAPK1 | |
| SCHEMBL2930366 | 0.82 | MAPT (0.71) | MAPTLMNASERPINA6CYP3A4MEN1 | |
| SCHEMBL13804528 | 0.82 | MAPT (0.71) | MAPTLMNASERPINA6CYP3A4MEN1 | |
| SCHEMBL17302789 | 0.82 | MAPT (0.71) | MAPTLMNASERPINA6CYP3A4MEN1 | |
| SCHEMBL13177160 | 0.82 | MAPT (0.71) | MAPTLMNASERPINA6CYP3A4MEN1 | |
| SCHEMBL13415930 | 0.80 | CYP17A1 (0.52) | MAPTLMNASERPINA6CYP3A4MEN1 | |
| SCHEMBL28509865 | 0.78 | SERPINA6 (0.62) | MAPTLMNASERPINA6CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1128810-A1 | DRUG DELIVERY DEVICE, ESPECIALLY FOR THE DELIVERY OF ANDROGENS | LEIRAS OY (FI) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000028967-A1 | DRUG DELIVERY DEVICE, ESPECIALLY FOR THE DELIVERY OF ANDROGENS | LEIRAS OY (FI) | 2000-05-25 | — | — | WO | disclosed |