SCHEMBL7777127

SCHEMBL7777127

CCOC(=O)C(CCC(C)C)(CCC1CCCC1)C(=O)OCC

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
MMP8 P22894 1/20 0.35
MMP2 P08253 1/20 0.33
BMP1 P13497 1/20 0.33
BCHE P06276 1/20 0.33
CTSK P43235 2/20 0.32
CCR2 P41597 1/20 0.32
CTSL P07711 1/20 0.32
CTSB P07858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7782648 0.93 METAP2 (0.41) METAP2KMT2AMEN1HPGDHTT
SCHEMBL7785266 0.89 KMT2A (0.49) METAP2KMT2AMEN1HTT
SCHEMBL7781964 0.88 MEN1 (0.47) METAP2KMT2AMEN1HPGD
SCHEMBL7785264 0.88 MEN1 (0.47) METAP2KMT2AMEN1HPGD
SCHEMBL234357 0.84 MEN1 (0.53) KMT2AMEN1HPGDHTTMMP8
SCHEMBL7781971 0.83 MMP8 (0.44) METAP2KMT2AMEN1HPGDHTT
SCHEMBL8331270 0.80 MEN1 (0.40) METAP2KMT2AMEN1
SCHEMBL7781947 0.79 MEN1 (0.49) KMT2AMEN1HPGDHTTMMP8
SCHEMBL28077465 0.77 MEN1 (0.46) KMT2AMEN1HPGDHTTMMP8
SCHEMBL7781952 0.77 MMP8 (0.50) KMT2AMEN1HPGDHTTMMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1141044-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER Basell Technology Company B.V. (NL) 2001-10-10 EP disclosed
WO-2001036496-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-05-25 WO disclosed